Items |
Standard |
Appearance |
Yellow crystalline powder. |
Characters |
Soluble in water,slightly soluble in ethanol(96 percent),practically insoluble in acetone. |
A TLC |
Conform to the reference. |
B Chlorides |
Reaction of chlorides. |
C Color Reaction |
To about 2mg add 5ml of sulphuric add the solutio to 2.5ml of water.The color becomes yellow. |
Acidity(pH) |
1.8~2.8 |
Specific optical rotation(dried substance) |
-240°~-255° |
Loss on drying |
≤2.0% |
Heavy metals |
≤50ppm |
Sulphated ash |
≤0.5% |
4-Epitetracyline |
≤3.0% |
4-Epianhydrotetracycline |
≤0.5% |
Anhydrotetracycline |
≤0.5% |
2-Acetyl-2-decarbamoyltetracycline |
≤1.5% |
Assay |
95.0%~102.0% |
Acetone(G.C.) |
≤100ppm |
N-butanol(G.C.) |
≤3000ppm |
TAMC |
103cfu/g |
TYMC |
102cfu/g |
E.coli |
Absence |