Items | Standard |
Appearance | Yellow crystalline powder. |
Characters | Soluble in water,slightly soluble in ethanol(96 percent),practically insoluble in acetone. |
A TLC | Conform to the reference. |
B Chlorides | Reaction of chlorides. |
C Color Reaction | To about 2mg add 5ml of sulphuric add the solutio to 2.5ml of water.The color becomes yellow. |
Acidity(pH) | 1.8~2.8 |
Specific optical rotation(dried substance) | -240°~-255° |
Loss on drying | ≤2.0% |
Heavy metals | ≤50ppm |
Sulphated ash | ≤0.5% |
4-Epitetracyline | ≤3.0% |
4-Epianhydrotetracycline | ≤0.5% |
Anhydrotetracycline | ≤0.5% |
2-Acetyl-2-decarbamoyltetracycline | ≤1.5% |
Assay | 95.0%~102.0% |
Acetone(G.C.) | ≤100ppm |
N-butanol(G.C.) | ≤3000ppm |
TAMC | 103cfu/g |
TYMC | 102cfu/g |
E.coli | Absence |